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Immunocompromised individuals, patients with central venous catheters, those with severe acute pancreatitis, and people with short bowel syndrome should avoid probiotics without medical supervision

On the other hand, adherence remains a critical factor

Amino Acids 40:12211229 Everaert I, De Naeyer H, Taes Y et al (2013) Gene expression of carnosine-related enzymes and transporters in skeletal muscle

That often includes medically supervised detox, therapy approaches like CBT and DBT, and strong family involvement to rebuild trust and communication

These conditions are often linked to chronic diseases, such as diabetes and heart disease, which can increase healthcare costs, lower productivity, and raise absenteeism

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